What's new in Guillain-Barré syndrome in 2007-2008?

Detection of Autoantibodies against Gangliosides in Guillain-Barré Syndrome

[Guillain Barré syndrome in pediatrics].

This paper reviews the current knowledge about Guillain-Barré syndrome (GBS). GBS is defined as an acute, areflexic, flaccid paralysis, which is classified into 4 subgroups: acute inflammatory demyelinating polyneuropathy (AIDP), acute motor-sensory axonal neuropathy (AMSAN), acute motor axonal neuropathy (AMAN) and Miller-Fisher syndrome (MFS). AIDP is associated in 30-50% of cases with crania...

Prognosis in Guillain-Barré syndrome.

Clinical recovery started in 23 children with Guillain-Barré syndrome after a mean time of 19 days and to full recovery in 15 was 6.2 months. Long term follow up indicated that 19 with acute onset had completely recovered clinically and three with subacute onset had a chronic relapsing or protracted course.

Guillain-Barré syndrome in pregnancy.

Guillain-Barré syndrome (GBS) complicating pregnancy is a rare event. Reports before the mid-1980s suggested that GBS in pregnancy carries a high maternal morbidity and mortality. However, it is uncertain whether availability of active treatment such as plasmapheresis and intravenous immunoglobulin together with advancement in intensive care has improved maternal outcome. This review examines t...

Prognosis in Guillain-Barré syndrome.

The case-records of 71 patients from previous therapeutic trials were used to determine features in clinical presentation that might be useful in predicting the outcome of the Guillain-Barré syndrome. The major features adversely affecting prognosis were severe maximum deficit requiring ventilation and failure to improve within 3 weeks of reaching peak deficit. The risk of poor outcome in a pat...